The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment
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General Radiology - Review

The role of dynamic contrast-enhanced MRI in cancer diagnosis and treatment

Diagn Interv Radiol 2010;16(3):186-192 DOI: 10.4261/1305-3825.DIR.2537-08.1
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Abstract

Angiogenesis is a key step in the pathophysiology of tumor growth and metastatic spread. Recently, dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has emerged as a method for assessing angiogenesis both during the initial diagnosis and for follow up of anti-angiogenic therapies. In this review, we discuss the technical aspects of implementing DCE-MRI in clinical practice with emphasis on acquisition methods and analytic techniques.

Keywords: pathologic angiogenesis, angiogenic inhibitors, magnetic resonance imaging