E-ISSN: 1305-3612
Evaluation of the splenic vein diameter and longitudinal size of the spleen in patients with Gamna-Gandy bodies
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Current Issue: 2022, Volume 32, Issue 3
VOLUME: 12 ISSUE: 3
P: 125-128
September 2006

Evaluation of the splenic vein diameter and longitudinal size of the spleen in patients with Gamna-Gandy bodies

Diagn Interv Radiol 2006;12(3):125-128
Nuray Haliloğlu Ünsal 1
Ayşe Erden 2
İlhan Erden 3
1. From the Department of Radiology, Ankara University, School of Medicine, Ankara, Turkey
2. Departments of Radiology, Ankara University School of Medicine, Ankara, Turkey
3. Department of Radiology, Ankara University School of Medicine, Ankara, Turkey
No information available.
No information available
Received Date: 12.05.2006
Accepted Date: 27.06.2006
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ABSTRACT

PURPOSE

The aim of this retrospective study was to compare the splenic vein diameter and longitudinal size of the spleen in patients with portal hypertension in whom Gamna-Gandy bodies were present in their spleen with those of cirrhotic patients without Gamna-Gandy bodies and a control group.

MATERIALS AND METHODS

Between July 2001 and February 2006, patients in whom Gamna-Gandy bodies were detected in their spleen and the number of patients who had been undergone magnetic resonance (MR) imaging with the diagnosis of chronic liver disease were determined. A total of 43 cases with Gamna-Gandy bodies were noted. Out of these patients, a case of lymphoma was excluded from the study. Additional 3 cases with splenic vein thrombosis were not included in statistical analysis. Accordingly, the splenic vein diameter and longitudinal size of the spleen in 39 patients (group 1: 12 women, 27 men; mean age, 38.5 years) with portal hypertension in whom Gamna-Gandy bodies were detected in their spleen on T1-weighted gradient-echo MR images between July 2001 and February 2006 were measured. The values obtained were compared with those of 29 cirrhotic patients without Gamna-Gandy bodies (group 2: 14 women, 15 men, mean age 48.2 years) and control group (group 3: 13 women, 18 men, mean age 46.8 years). The differences between the groups were analyzed with ANOVA and student-t test.

RESULTS

Gamna-Gandy bodies were detected in 6.3% (42/670) of patients with chronic liver disease. The mean longitudinal axis of the spleen (20.2±4.2 cm) in group 1 was significantly greater (p<0.001) than in group 2 (14.4±3.9 cm). The mean splenic vein diameter was significantly larger in group 1 (14.3±4.0 mm) than those in groups 2 and 3 (11.2±3.2 mm and 7.8±1.4 mm, respectively).

CONCLUSION

The splenic vein diameter and longitudinal size of the spleen in portal hypertensive patients with Gamna- Gandy bodies are significantly larger than that of cirrhotic patients without Gamna-Gandy bodies and that of control group.